NAC stands for N-acetylcysteine. Chemically, it is a sulfur-containing amino acid derived from cysteine.
It is widely known for its ability to regulate the synthesis of glutathione and to form an enzyme called glutathione peroxidase, which acts as an important cellular detoxifying agent, capable of fighting off drugs, free radicals or toxic metabolic intermediates. NAC is an antidote for paracetamol poisoning. Glutathione is present in all organs and tissues, so taking NAC can be beneficial for all organs and tissues. Taking NAC can be particularly beneficial for conditions such as neurodegeneration, chronic diabetes, cardiovascular or liver disease.
In addition, NAC helps reduce the levels of inflammatory cytokines by inhibiting the activity of NFKB and, consequently, the cytokines induced by this factor, such as TNF alpha, ILF6 and IL8. It also acts as a direct antioxidant against the radicals NO2, OH- and O2, helps reduce bacterial adhesion to the mucous membranes and supports mucolytic activity, which can eliminate bacterial and viral pathogens from the system. Due to these properties, it has a solid function in the treatment of respiratory diseases, obstructive pulmonary diseases and in the prevention of lung infections.
Taking NAC supports glutathione synthesis and lowers the concentration of homocysteine, which is considered an important cardiovascular risk factor. An interesting study has confirmed that taking NAC for one month can reduce homocysteine concentration by 28%.
